N-Fmoc-L-glutamic acid 5-allyl ester
fmoc-L-glutamic acid 5-allyl ester
CAS: 133464-46-7
Molecular Formula: C23H23NO6
N-Fmoc-L-glutamic acid 5-allyl ester - Names and Identifiers
| Name | fmoc-L-glutamic acid 5-allyl ester |
| Synonyms | Fmoc-Glu(OAll)-OH FMOC-L-GLU(ALL)-OH FMOC-GLU(OALL)-OHFMOC-GL fmoc-L-glutamic acid 5-allyl ester FMOC-L-GLUTAMIC ACID 5-ALLYL ESTER N-Fmoc-L-glutamic acid 5-allyl ester FMoc-Glu(OAll)-OH FMoc-L-glutaMic acid γ-allyl ester 5-Allyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamate (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)-amino)-5-(allyloxy)-5-oxopentanoic acid (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxo-5-(prop-2-en-1-yloxy)pentanoic acid (non-preferred name) |
| CAS | 133464-46-7 |
| InChI | InChI=1/C23H23NO6/c1-2-13-29-21(25)12-11-20(22(26)27)24-23(28)30-14-19-17-9-5-3-7-15(17)16-8-4-6-10-18(16)19/h2-10,19-20H,1,11-14H2,(H,24,28)(H,26,27)/t20-/m0/s1 |
N-Fmoc-L-glutamic acid 5-allyl ester - Physico-chemical Properties
| Molecular Formula | C23H23NO6 |
| Molar Mass | 409.43 |
| Density | 1.264±0.06 g/cm3(Predicted) |
| Melting Point | 122 - 128°C |
| Boling Point | 650.1±55.0 °C(Predicted) |
| Flash Point | 347°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 8.69E-18mmHg at 25°C |
| Appearance | White powder or crystal |
| Color | White |
| BRN | 6670846 |
| pKa | 3.70±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.585 |
| MDL | MFCD00190879 |
N-Fmoc-L-glutamic acid 5-allyl ester - Risk and Safety
| Risk Codes | R22/22 - R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S44 - S35 - This material and its container must be disposed of in a safe way. S28 - After contact with skin, wash immediately with plenty of soap-suds. S7 - Keep container tightly closed. S4 - Keep away from living quarters. |
| WGK Germany | 3 |
| HS Code | 2924 29 70 |
N-Fmoc-L-glutamic acid 5-allyl ester - Introduction
N-fluorenylmethoxycarbonyl-L-glutamic acid 5-allyl ester, commonly known as FMOC-L-Glutamic Acid 5-Tert-butyl Ester, is an organic compound.
Its chemical formula is C25H27NO7 and its molecular weight is 453.48g/mol. It is a white to off-white solid, soluble in some organic solvents such as dimethylformamide (DMF) and dichloromethane (DCM). Its melting point is about 75-82°C.
N-fluorenylmethoxycarbonyl-L-glutamic acid 5-allyl ester can be used for protecting and modifying groups in chemical synthesis. It can be introduced into amino acids or small peptide sequences to play a protective role. In the process of chemical synthesis, it can be used as an activator to replace with other compounds.
The method for preparing N-fluorenylmethyloxycarbonyl-L-glutamic acid 5-allyl ester usually involves protection and esterification of N-fluorenylmethyl-L-glutamic acid. First, the N-fluorenylmethyl-L-glutamic acid reagent is formed by protection with chlorotrimethylsilane (TMSCl). Then, the N-fluorenylmethyl-L-glutamic acid reagent was esterified with allyl alcohol to obtain the target product.
Regarding safety information, N-fluorenylmethoxycarbonyl-L-glutamic acid 5-allyl ester is relatively safe under correct use and storage. However, it is a chemical that may be toxic to humans. Therefore, in use should follow the correct laboratory procedures, and take appropriate safety measures.
Its chemical formula is C25H27NO7 and its molecular weight is 453.48g/mol. It is a white to off-white solid, soluble in some organic solvents such as dimethylformamide (DMF) and dichloromethane (DCM). Its melting point is about 75-82°C.
N-fluorenylmethoxycarbonyl-L-glutamic acid 5-allyl ester can be used for protecting and modifying groups in chemical synthesis. It can be introduced into amino acids or small peptide sequences to play a protective role. In the process of chemical synthesis, it can be used as an activator to replace with other compounds.
The method for preparing N-fluorenylmethyloxycarbonyl-L-glutamic acid 5-allyl ester usually involves protection and esterification of N-fluorenylmethyl-L-glutamic acid. First, the N-fluorenylmethyl-L-glutamic acid reagent is formed by protection with chlorotrimethylsilane (TMSCl). Then, the N-fluorenylmethyl-L-glutamic acid reagent was esterified with allyl alcohol to obtain the target product.
Regarding safety information, N-fluorenylmethoxycarbonyl-L-glutamic acid 5-allyl ester is relatively safe under correct use and storage. However, it is a chemical that may be toxic to humans. Therefore, in use should follow the correct laboratory procedures, and take appropriate safety measures.
Last Update：2024-04-10 22:29:15
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Product Name: Fmoc-Glu(OAll)-OH Visit Supplier Webpage Request for quotationCAS: 133464-46-7
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